Used to think and feel the 22-250 was the best for dog hunting, but learned its just a reason not to try anything else !!

I have many calibers do the job on dogs, none better now since I have a 204, simply has everything the 250 doesn’t.

Stays on target at high magnification, hardly a kick, awesome killing range, shoot solids it will not leave giant
Exits, nope 250 as far as Im concerned is now my lender rifle for bring alongs, no changing my mind don’t bother
Trying !!

I’ve shot a lot of coyotes with the Nosler 77 grain custom competition bullet with fairly good luck. Good wind bucking bullet and as long as you stay off major bone damage is fairly minimal.

Hunting buddy has a .204, still amazed at what that cartridge can do...Extremely accurate to boot.

I'll agree with ky on that one. But if I'm going to use a 22-250 I agree with you on bullet choice, Sierra GameKing softpoints. My 22 centerfires love V-Max bullets, super accurate, but I have figured out not to use them on anything but ground squirrels if I want to retrieve everything I shoot. Plus they are often far from fur friendly.

If I was buying a gun specifically for coyote hunting it would probably be a 243. I don't own one, but have seen good results with them, and with the right bullets they are fairly fur friendly. I've shot coyotes with everything from 22 long rifle to 45/70 and overall have not been completely satisfied with any of the 22 calibers I have tried (22 lr, 22 mag, 22 Hornet, 218 Bee imp, 223, 22-250). Since I don't own a 24 or 25 caliber rifle, the 260 is what I grab, it anchors them, but you are going to be putting a few stitches in. Anything bigger than that is usually pretty rough on fur.

22-250 fur bullet was the question!
Nosler Ballistic Tip in 40 or 50 gr. depending on distance being shot. I like the 40 gr. but does drop off faster and wind has more effect on it than the 50gr. Fine fur bullet.
Mostly I shoot the Barnes Triple Shock 53 gr. Accurate, hits hard with small pass through hole. Cost is about twice of others. I am a believer in them.
I find the 22-250 does best with 40 - 55 gr. bullets at around 3650 fps + -. The lite ones can be pushed faster but accuracy suffers. 3600 - 3650 seems to be the sweet spot for the caliber.
Fairly sure Less Johnson shoots Hornady pills.

Most of the heavy .22 cal bullets are heavy jacketed types that will likely behave mostly like a FMJ.

Be prepared for lots of runners.

Agreed, I run my Amax’s right around 3600fps.

My three favorites are the 50 or 55 grain Nosler ballistic tips (NOTHING like a v-max), or the 52 grain Sierra HPs.

I don’t like v-max, blitzkings, varmint grenades, etc, especially the “lighter” ones.

Seems 3600-3650 is the sweet spot for terminal performance with the Noslers.

Just because you can throw them at 3900, doesn’t mean you should.

Nosler Bt's are purty good.

I am very pleased with the performance of the 36 grain Varmint Grenades. I was shooting them at an estimated 4200 ft/s. If you hit them head on or broadside in the chest there is no exit hole and it is instant death. It turns their insides to mush. If I want to keep the pelts, I wouldn’t pick anything else. Just like any bullet, if you hit a lot of bone, you will have damage. If you do your part and put the little Grenades where you want them, you will be pleased.

what boone said

I have been shooting Hornaday 55gr spiral points for decades. They do the job and bullet is commonly found under the hide on the far side.
Roy

Pelt wrecker

Of course in the current state of the market, who cares about fur damage?

They aren’t worth the sweet equity to get em back to the truck!

I used 52 gr. Speer Hollowpoints for years, they did good, still came down to shot placement. Finally settled on Nosler 55 gr ballistic tips. Did wonderful on Cats and Coyotes. Bought enough for the rest of my shooting days. Good for Turkey shoots too.

I shoot 45 and 50 gr jhp or lite jacketed sp bullets, pushing 3800/3900 fps; but my 22-250 has a 1:12 twist rate. I stay away from anything that has a piece of plastic shoved up it's nose, to much fur damage from rapid expansion in my personal opinion, that just me.

With the 1:9 twist you will need to use heavier projectiles. Too heavy a jacket and you'll be hunting with what acts like a solid, shots going straight through with little expansion, knocking them down but not putting them out. Slow velocity will be the key with the heavier bullets. Exit holes can be quite large especially if bone is shattered. If your firearm will shoot the 55 or 60 gr HP that's what I would chose to use. But, YMMV.

Yeppers so all I feel after wracking em with my .220 swift is a bit of recoil.

If I was competition calling I would use my old 270. not a lot of recoil and it bucks the wind better

.22-250 - 45 gr white box Winchester HP for me. I've see very little fur damage at any ranges with one notable exception but it was a mangy dog anyway.

How much better Danny.
I've shot several sub 1" 4 shot groups at 300 yards with a plain Jane Savage 25itty.
Your .270 do that?..didn't think so.