Why is it one brand hits dead on but put something different and often times they hit off to the right or left?

I get missing up and down with different bullet weights and powders. Just don't understand the side..

Barrel harmonics

X 2

^^^X3^^^

Barrel harmonics but when you consider all the possible variables of primer, brass, powder, charge weight, charge position, ambient temperature, neck thickness, neck tension, chamber fit, bullet alignment, bullet construction, ad infinitum, and it's amazing any load is accurate.

In my .30-06 Vanguard, same bullet, case, powder and primer, as the load gets hotter (more vel), the POI moves up and to the right. No surprise changing factory ammo changes POI.

Ive seen slower charges shoot higher. Just depends on where the barrel is pointed when the bullet leaves the barrel

Or sometimes when working up a load you change only the brand of primer and group size really tightens up.

Yep

My 17WSM is a tack driver until the barrel gets warm.

Mainguy, If the sling stud swivel is touching the barrel
that can be a problem.

x34 music lessons lol

Do your bows do this?

Most extreme case of this I've ever seen, I was messing around one day and loaded some subsonic 500 grain loads for my 45/70. They grouped over a foot higher at 25 yards than my regular 405 grain hunting loads. While full power 500 grain loads hit within an inch of my 405 loads.

Back to the original question, I have some Scirroco's I've loaded in a 260 for hunting, they shot about 2 MOA right of either the couple factory loads I've shot through it (one hunting, one target) or the target loads I've loaded for it. Since that is the gun the wife shoots, it really frustrates her when I give her the (much cheaper) target loads to plink and practice with and it keeps hitting left of the target.

You know that every ammo company uses different components, and recipes....right?

Different brass
Different primer
Different powder
Different volume of powder.