They cover this in the full Joe Rogan interview. That's how they did it, but it sounds like it's all with genes that dire wolves contained. They aren't recreating a specific dire wolf, but a combination of 2 dire wolves, which have most of the same genes as gray wolves.

Keith

So its a GMO grey wolf?

They are GMO dire wolves. Genetically Modified Organisms are not usually anything to be scared off. The genes they selected, could have combined in nature if dire wolves were still around.

People could make terrible GMO organisms, but they can make incredibly beneficial GMO organisms too.

Keith

From what I've been reading gray wolves and dires aren't actually all that close genetically. The scientists based their work on a partially sequenced dire genome from the two fossil samples Keith mentioned. They made 20 edits on 14 genes that would give dire characteristics to a gray wolf donor egg.

What they produced was a gray wolf with some dire characteristics.

Mixing of species is what the fallen angels did. Disregard it, call it myth, call it BS, what have you.......

But there are accounts of this very thing going on that we can read about and the result did not end well.

They removed all genetic material from the gray wolf egg.

Keith

I don't believe that is correct. They said the work they did was to make 20 edits on 14 genes. That would leave all the rest original gray wolf genes.

Either way, to think bringing back more apex predators is a good thing for hunters and trappers is crazy.

They are talking about dodo birds and saber tooth tigers. Can you imagine a saber tooth tiger? What a freaking great idea!!!

Not to be picking on you Keith, but if you look into it a bit further H. sapiens sapiens are thought to have had a one gene mutation that produced extra neurons in the neocortex. This is associated with more intelligence. Neanderthal did not have the mutation.

Sabre toothed tiger info. Imagine!!

https://biologydictionary.net/saber-tooth-tiger/

You watched jurassic park too many times man!

So how about the tasmanian tiger?

https://www.scientificamerican.com/...y-aims-to-resurrect-the-tasmanian-tiger/

And other ambitions.

https://listverse.com/2023/03/23/10-ambitious-projects-aimed-at-resurrecting-extinct-animals/

My radar is up and pinging about this company and it's ties to animal rights organizations. Bringing back apex predators IS NOT a good idea.

If you think cougars kill a lot of animals, imagine the appetite of one that weighs 5X more.

Colossus CEO was just on the Glenn Beck show to present what they were doing.

I'm a litlte suprised to see some prey animals on that list. I've seen comments about people buying game bird chicks (quail, etc) and how that often just works out being very expensive predator food because when raised in captivity they don't learn the paranoid behavior necessary to survive in the wild. As I understand it, a large part of prey animal's survival, comes from the learned behaviors watching their parents in the wild.

I could see how bringing back an apex preditor might have a higher chance of success because when a young preditor makes a mistake, they're hungry. Whereas when a young prey animal makes a mistake it is dead.

I'm not a fan of any of it. I have the same concerns y'all have been mentioning. Just pointing out there's likely an extra set of challenges releasing prey animals in the wild.

The eggs used have all genetic material removed.

"They then took the genetic material from this cell and placed it into the egg cell of a domesticated dog that had had its genetic material removed. Once that egg cell had developed into an embryo, it was implanted into a surrogate dog."

Much of the DNA of a gray wolf is also present in dire wolves, just like much of the DNA in a Chimpanzee is present in humans.

https://www.wired.com/story/scientists-brought-back-dire-wolf-deextinct/

Keith

Animal rights activist would get it put on the endangered list so we wouldn't be able to hunt or trap them without any federal repercussions.

Carl, the mystery population referred to is believed to be Homo sapiens that left Africa and interbred with Homo neanderthalensis, in Turkey and the Caucus, by a great many anthropologists.



Keith

A gray wolf has about 19,000 genes. 14 genes we're edited for 20 total edits. All the rest of the genetic makeup of dire/gray wolf hybrid puppies had to have come from the gray wolf donor egg. Where else would it come from?