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They edited the DNA of grey wolves with DNA from long extinct dire wolves. So I expect its more accurate to say its a grey/dire cross, but still interesting. There are 3 puppies. 2 male, one female.
Perfect, I think they should establish the first population of them on Mercer Island (where Bill Gates lives), a suburb of Seattle. Lots of prey species in that area.
"My life is better than your vacation"
Re: Dire Wolves cloned (extinct thousands of years)
[Re: KeithC]
#8382132 04/07/2504:09 PM04/07/2504:09 PM
They could quickly kill the dire wolves with drones, in the absurd chance they ever became a problem.
Keith
nope 9 protests and 7 judges and 14 injunctions , they will claim they are a native species , endangered and we should all offer ourselves as sacrifices to feed and keep them going even though they have been extinct 10000 years
America only has one issue, we have a Responsibility crisis and everything else stems from it.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382139 04/07/2504:23 PM04/07/2504:23 PM
Keith, I used to eat at a restaurant in eastern Ecuador that we volunteers dubbed the endangered species restaurant. You would have loved it. Capybara, tapir, caiman, agouti, giant amazonian catfish...etc.
My favorite hands down was agouti.
Last edited by beaverpeeler; 04/07/2505:51 PM.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382204 04/07/2506:00 PM04/07/2506:00 PM
Perfect, I think they should establish the first population of them on Mercer Island (where Bill Gates lives), a suburb of Seattle. Lots of prey species in that area.
I was thinking New York City a lot of rats there to eat.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382287 04/07/2507:29 PM04/07/2507:29 PM
I think dire wolves will be a non issue for us. It's interesting technology, which is likely going to be used mostly to make superior meat animals, show animals and pets.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382475 04/07/2510:04 PM04/07/2510:04 PM
The organic crowd frowns upon gene editing but I actually think it's pretty cool. I would pay good money to see a wooly mammoth. How much could they charge for wooly mammoth rides at the game park?
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: beaverpeeler]
#8382496 04/07/2510:21 PM04/07/2510:21 PM
Keith, I used to eat at a restaurant in eastern Ecuador that we volunteers dubbed the endangered species restaurant. You would have loved it. Capybara, tapir, caiman, agouti, giant amazonian catfish...etc.
My favorite hands down was agouti.
That would be a fun restaurant to go to.
Agouti look like they would be very good to eat. They sell a lot of agouti at the Mt. Hope Exotic Sale. Most are sold for Santeria. I know a guy who bought 37 agouti to resell in Florida for Santeria.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: k snow]
#8382504 04/07/2510:43 PM04/07/2510:43 PM
Read most of the article. These people think they are controlling the fate(s) of species. Good luck with that.
A 2,000 acre enclosure surrounded by a 10 foot fence. Sounds like a recipe for disaster.
How long before one of the "Free the Mink" nut cases cuts the fence so they can run free?
The dire wolves were bottle fed by people and around dozens of people daily. I don't think catching them would take much of a trapper. They are probably less trap shy then an opossum drunk on fermented fruit.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382548 04/08/2512:20 AM04/08/2512:20 AM
I agree with Warrior 100% that all research needs to be stopped and destroyed. Put an end to it. The DOD is probably funding this nonsense, just like they funded the chimera nonsense and probably the Covid BS.
The "rewilding" scientists are some lunatic dangerous people. Nothing good will come of this.
Resident Conspiracy Theorist Accused Moron, Nazi, Low IQ, Putin Fan Boy, and Obama Clone
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382584 04/08/2501:52 AM04/08/2501:52 AM
There is only 3 now but wait a few years when they turn them loose in Yellowstone. They will kill everything including visitors, all while being protected. Then you have the wooly mammoth and the Sabre tooth tiger.man, I'm glad I'm 70.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382751 04/08/2511:09 AM04/08/2511:09 AM
My thoughts exactly Rat_Pack. I figured the first place they'd be reintroduced would be the Timbers of Fenario.
In all seriousness though, I can agree with many in saying that I don't think any good will come of this work. I breakfasted with a couple of Colossal's geneticists earlier this year, and while the individuals were decent enough people (as most people tend to be), I can't say that I like their goals. Part of me wonders if the "coolness factor" of being able to de-extinct (as they put it) fun animals combined with the sentimentality of undoing the perceived wrongs of humanity (in causing the extinction of some species) which plays very well to the public mood these days, are really just ways to get the money they want to further develop gene-editing and cloning technology. Then again, maybe their motives are genuine. Either way, I don't see that humans wielding that kind of power will be a good thing. Humanity has a penchant for abusing any power it obtains.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382885 04/08/2502:43 PM04/08/2502:43 PM
people often equate the ability to manipulate something for having the ability to control. Its easy confuse the two because manipulation often looks like control, right up until things get ugly. The longer someone gets away with manipulation, the more they think they're in control.
For example, Immediately before a government is overthrown, they're often yanking people around thinking their ability to manipulate people is the same as being able to control.
Humans certainly have gained the ability to manipulate DNA. But the consequences (even of the individual changes they make) are not fully understood, and that manipulation is not equivalent to control.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382911 04/08/2503:54 PM04/08/2503:54 PM
Those wolves were designed to eat large mega fauna from the ice age, mammoths, giant bison etc.. those went missing so the dire wolves ran out of food and followed them. I guess they could finish off whatever elk, moose and buffalo thats still around, but that shouldn't take long with any amount of re wilded Dire wolves
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8382982 04/08/2506:15 PM04/08/2506:15 PM
people often equate the ability to manipulate something for having the ability to control. Its easy confuse the two because manipulation often looks like control, right up until things get ugly. The longer someone gets away with manipulation, the more they think they're in control.
For example, Immediately before a government is overthrown, they're often yanking people around thinking their ability to manipulate people is the same as being able to control.
Humans certainly have gained the ability to manipulate DNA. But the consequences (even of the individual changes they make) are not fully understood, and that manipulation is not equivalent to control.
No offense, but did your speech writer suddenly become available to you since this past November? (Okay, maybe a tiny bit of offense was meant, but nothing personal, well not really personal since we have never met.)
Re: Dire Wolves cloned (extinct thousands of years)
[Re: beaverpeeler]
#8383129 04/08/2508:23 PM04/08/2508:23 PM
No offense, but did your speech writer suddenly become available to you since this past November? (Okay, maybe a tiny bit of offense was meant, but nothing personal, well not really personal since we have never met.)
No I've had that thought for a long time. The political illustration was an afterthought I threw in before clicking 'Post Reply'. With the political illustration I was thinking of actual overthrowing of governments like when kings loose their heads and such. Nothing in November crossed my mind until readding your reply. If it matters to you, I wrote in Mike Pence in the '24 general election.
Another view I've had for a long time has to do with the word assume being self descriptive. But that thought isn't my own, I heard it from others long ago.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383207 04/08/2509:31 PM04/08/2509:31 PM
If 19-20 genes were the only difference between the dire and the grey then they have duplicated 100% the dire. My understanding is they were able to sequence several ancient dire fossils genomes.
Last edited by beaverpeeler; 04/08/2510:00 PM.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383261 04/08/2509:58 PM04/08/2509:58 PM
they could work on a better cure to cancer with that money and not a new super predator
I guess at least a regular 308win should take down a Dire wolf[/quote] I think even just a .243 would be fine, but I'd go with a .270 or .308, just in case.[/quote]
22mag with FMJ’s
If you take care of the land the land will take care of you
Re: Dire Wolves cloned (extinct thousands of years)
[Re: bowhunter27295]
#8383314 04/08/2510:58 PM04/08/2510:58 PM
Well there are several on here that I would swear have been genetically spliced with Cromagnons.
Cro-magnons were some of the first smarter Homo sapiens resulting from interbreeding with Neanderthals. Homo sapiens without Neanderthal DNA, have statistically much lower IQs. Higher intelligence developed outside of Africa, probably in large part from adaptation to harsher living conditions.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383328 04/08/2511:32 PM04/08/2511:32 PM
That neanderthal interbreeding with Homo sapiens sapiens made them smarter, well, I would like to see the supporting science. Larger cranial capacity doesn't necessarily translate to more smarts.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383348 04/09/2512:14 AM04/09/2512:14 AM
Neanderthals are believed to have had the same average IQ range as modern humans, of 85 to 115, with a mean of 100 compared to the mean average IQ of Sub Saharan Africans, the first Homo sapiens, which is 82.
Larger brain size has a slight correlation to intelligence. Likely the biggest reason for higher intelligence in Neanderthals is genetic selection from living in a harsher environment.
The areas of Africa with Neanderthal genetics have higher average IQs than the Sub Saharan parts of Africa.
I doubt there is a single person on this forum who doesn't have Neanderthal DNA.
Caucasians and Asians all have Neanderthal DNA, with some Asians having a fair amount of Denisovan DNA. Almost all black people in the US have Neanderthal DNA too.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383351 04/09/2512:23 AM04/09/2512:23 AM
There’s a project planned to repopulate woolly mammoths into northern Siberia. Given the lack of megafauna, scientists suspect that the vegetation is impacting the climate a certain way. The thought is that woolly mammoths’ feeding habits will help to return the Siberian vegetation to a more desirable state.
I wonder if the dire wolves are being raised as a secondary part of the project. Perhaps a control mechanism on mammoth populations?
Re: Dire Wolves cloned (extinct thousands of years)
[Re: Bob_Iowa]
#8383359 04/09/2512:59 AM04/09/2512:59 AM
Would anybody be open to bringing back recently gone-extinct critters... ie: passenger pigeon?
I was thinking something like that or the dodos that were killed and made extinct directly by humans.
I'm not in favor of any of it. Even in the case of the dodo and Thylacine. I don't agree with any of it. Especially the madness behind it. Those rewilding scientists are mad. I think many of them would rather see current human extermination and give it back to animals.
But since we are on the subject........Why not bring back the native populations of people that were made extinct directly by humans long before we bring any critters back. Again, I am against all of it.
Resident Conspiracy Theorist Accused Moron, Nazi, Low IQ, Putin Fan Boy, and Obama Clone
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383362 04/09/2502:39 AM04/09/2502:39 AM
If they can bring back the sloths, horses, mammoths and camels that made up most of the prey base they can make a nice game park. We can put them on Greenland once we acquire it.
Last edited by beaverpeeler; 04/09/2510:58 AM.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383552 04/09/2510:59 AM04/09/2510:59 AM
Hey look, we did the same things with Conservatives in the 2024 election. They had long since been dead but we took some Reagan DNA and mixed it with a guy that actually had a spine and . . . . Ta Da!!! Conservatives can once again be heard howling.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383561 04/09/2511:09 AM04/09/2511:09 AM
If they can bring back the sloths, horses, mammoths and camels that made up most of the prey base they can make a nice game park. We can put them on Greenland once we acquire it.
What an Idea
Or Manitoba
NRA and NTA Life Member www.BackroadsRevised@etsy.com
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383585 04/09/2511:24 AM04/09/2511:24 AM
What if the Dire Wolf carries a disease that affects wild and domestic canines. Or a bad gene that is passed on to other canines. Just because something is no longer here because of extinction, doesn't necessarily mean that it wouldn't have died off on its own... or that it should be brought back. Maybe the passenger pigeon was the biggest carrier of bird flu... if that's the case, why would we want it back?
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383591 04/09/2511:36 AM04/09/2511:36 AM
I've read a couple of contradicting versions of this work now. One of them states that the complete genome of the dire wolf was never sequenced and that the scientists doing the work on the project chose a certain number of genes to manipulate that had to do with phenotype (what the wolf looked like). No actual dire dna was inserted into the gray wolf ovum, just the instructions rewritten on 19 genes.
That being the case it isn't truly a 100% dire. It's a gray-dire hybrid.
Last edited by beaverpeeler; 04/09/2511:37 AM.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: warrior]
#8383598 04/09/2511:51 AM04/09/2511:51 AM
I've read a couple of contradicting versions of this work now. One of them states that the complete genome of the dire wolf was never sequenced and that the scientists doing the work on the project chose a certain number of genes to manipulate that had to do with phenotype (what the wolf looked like). No actual dire dna was inserted into the gray wolf ovum, just the instructions rewritten on 19 genes.
That being the case it isn't truly a 100% dire. It's a gray-dire hybrid.
They cover this in the full Joe Rogan interview. That's how they did it, but it sounds like it's all with genes that dire wolves contained. They aren't recreating a specific dire wolf, but a combination of 2 dire wolves, which have most of the same genes as gray wolves.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: KeithC]
#8383655 04/09/2501:18 PM04/09/2501:18 PM
I've read a couple of contradicting versions of this work now. One of them states that the complete genome of the dire wolf was never sequenced and that the scientists doing the work on the project chose a certain number of genes to manipulate that had to do with phenotype (what the wolf looked like). No actual dire dna was inserted into the gray wolf ovum, just the instructions rewritten on 19 genes.
That being the case it isn't truly a 100% dire. It's a gray-dire hybrid.
They cover this in the full Joe Rogan interview. That's how they did it, but it sounds like it's all with genes that dire wolves contained. They aren't recreating a specific dire wolf, but a combination of 2 dire wolves, which have most of the same genes as gray wolves.
Keith
So its a GMO grey wolf?
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8383687 04/09/2502:16 PM04/09/2502:16 PM
They are GMO dire wolves. Genetically Modified Organisms are not usually anything to be scared off. The genes they selected, could have combined in nature if dire wolves were still around.
People could make terrible GMO organisms, but they can make incredibly beneficial GMO organisms too.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8384022 04/09/2511:07 PM04/09/2511:07 PM
From what I've been reading gray wolves and dires aren't actually all that close genetically. The scientists based their work on a partially sequenced dire genome from the two fossil samples Keith mentioned. They made 20 edits on 14 genes that would give dire characteristics to a gray wolf donor egg.
What they produced was a gray wolf with some dire characteristics.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8384045 04/10/2512:04 AM04/10/2512:04 AM
From what I've been reading gray wolves and dires aren't actually all that close genetically. The scientists based their work on a partially sequenced dire genome from the two fossil samples Keith mentioned. They made 20 edits on 14 genes that would give dire characteristics to a gray wolf donor egg.
What they produced was a gray wolf with some dire characteristics.
They removed all genetic material from the gray wolf egg.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8384243 04/10/2510:23 AM04/10/2510:23 AM
Neanderthals are believed to have had the same average IQ range as modern humans, of 85 to 115, with a mean of 100 compared to the mean average IQ of Sub Saharan Africans, the first Homo sapiens, which is 82.
Larger brain size has a slight correlation to intelligence. Likely the biggest reason for higher intelligence in Neanderthals is genetic selection from living in a harsher environment.
The areas of Africa with Neanderthal genetics have higher average IQs than the Sub Saharan parts of Africa.
I doubt there is a single person on this forum who doesn't have Neanderthal DNA.
Caucasians and Asians all have Neanderthal DNA, with some Asians having a fair amount of Denisovan DNA. Almost all black people in the US have Neanderthal DNA too.
Keith
Not to be picking on you Keith, but if you look into it a bit further H. sapiens sapiens are thought to have had a one gene mutation that produced extra neurons in the neocortex. This is associated with more intelligence. Neanderthal did not have the mutation.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8384249 04/10/2510:29 AM04/10/2510:29 AM
I'm a litlte suprised to see some prey animals on that list. I've seen comments about people buying game bird chicks (quail, etc) and how that often just works out being very expensive predator food because when raised in captivity they don't learn the paranoid behavior necessary to survive in the wild. As I understand it, a large part of prey animal's survival, comes from the learned behaviors watching their parents in the wild.
I could see how bringing back an apex preditor might have a higher chance of success because when a young preditor makes a mistake, they're hungry. Whereas when a young prey animal makes a mistake it is dead.
I'm not a fan of any of it. I have the same concerns y'all have been mentioning. Just pointing out there's likely an extra set of challenges releasing prey animals in the wild.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: beaverpeeler]
#8384344 04/10/2501:41 PM04/10/2501:41 PM
I don't believe that is correct. They said the work they did was to make 20 edits on 14 genes. That would leave all the rest original gray wolf genes.
The eggs used have all genetic material removed.
"They then took the genetic material from this cell and placed it into the egg cell of a domesticated dog that had had its genetic material removed. Once that egg cell had developed into an embryo, it was implanted into a surrogate dog."
Much of the DNA of a gray wolf is also present in dire wolves, just like much of the DNA in a Chimpanzee is present in humans.
Carl, the mystery population referred to is believed to be Homo sapiens that left Africa and interbred with Homo neanderthalensis, in Turkey and the Caucus, by a great many anthropologists.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: KeithC]
#8384425 04/10/2504:18 PM04/10/2504:18 PM
I don't believe that is correct. They said the work they did was to make 20 edits on 14 genes. That would leave all the rest original gray wolf genes.
The eggs used have all genetic material removed.
"They then took the genetic material from this cell and placed it into the egg cell of a domesticated dog that had had its genetic material removed. Once that egg cell had developed into an embryo, it was implanted into a surrogate dog."
Much of the DNA of a gray wolf is also present in dire wolves, just like much of the DNA in a Chimpanzee is present in humans.
A gray wolf has about 19,000 genes. 14 genes we're edited for 20 total edits. All the rest of the genetic makeup of dire/gray wolf hybrid puppies had to have come from the gray wolf donor egg. Where else would it come from?
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8384445 04/10/2505:10 PM04/10/2505:10 PM
Carl, my understanding is that the other genes are shared between the two species and therefore would not need edited. Just like if you were making a person.out of an orangutan sample, you would only need to edit the few genes that are different to do so.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8384522 04/10/2507:15 PM04/10/2507:15 PM
Our ancestors went to a lot of trouble to kill mammoths. Probably cause it was such an enormous amount of food and tool resources. Maybe cause they were delicious. If they make a sort of copy I wonder how much a steak will cost?
Those who would give up essential liberty, to purchase a little temporary safety, deserve neither liberty nor safety. Benjamin Franklin (1706-1790)
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8384811 04/11/2507:15 AM04/11/2507:15 AM
Carl, my understanding is that the other genes are shared between the two species and therefore would not need edited. Just like if you were making a person.out of an orangutan sample, you would only need to edit the few genes that are different to do so.
Keith
There are lots of more or less significant differences in most of the shared genes, since the two species aren't very close. However, most of these differences don't affect the phenotype, plus many genes seem to have no (known) function whatsoever. Figuring out which genes do affect the phenotype is a big challenge.
A sequenced genome and actual DNA in a live cell are two very different things.
Full-genome sequencing means a bunch of DNA is extracted (from fossils, in this case) and read, and if it's well-preserved, i.e. if there are plenty of fragments, say, over 10 000 base pairs long, it can be assembled into a genome by supercomputers without too many mistakes, usually using a reference genome of a related species as a helpful template. A wolf genome is about 2.5 billion base pairs long. There are plenty of repeating fragments, so smaller pieces cause more mistakes. A rough comparison would be, you can restore text reatively easily and accurately if you have a dozen identical books cut up into random fragments ranging from a paragraph to a couple of pages, but not if they are cut up into pieces 2-3 words long. So that sequenced DNA is a computer file. Essentially a text with some formatting. Fancy formatting if it's a modern chromosome-level assembly, nevertheless. A long way from actual DNA.
We can compare the dire wolf text with the wolf text, find the corresponding genes, assemble ("cook", in a lab) short fragments repesenting the differences in specific genes, and replace the corresponding stretches of DNA from a fresh wolf cell with dire wolf variants using the CRISPR-Cas9 "scissor" enzyme. So technically, they are regular wolves with several dire wolf genes copypasted into ther genome. Similarly, the "mammoths" they are hoping to "reconstruct" will be hairy elephants with perhaps a few other select mammoth phenotype traits.
None of the technologies that were used are brand new, but it's a lot of good work, and a lot of money. Pinpointing specific genes responsible for specific phenotypical traits is tedious and expensive. In fact, Colossal's previous creation, the mammoth mice, was probably a bigger challenge, technologically, but less PR-worthy. These technologies are routinely used in labs around the world but it's usually with very unimpressive creatures such as fruit flies.
And these wolves being put on "endangered" lists or released into the wild seems like a far-fetched concern since formally they are lab animals, and animal rights fascists (or rather, the budget thieves they are employed by) have plenty of other, legally easier options for actual wild animals (orcas, wolves, sea otters, etc) to weaponize = monetize.
Your scientific explanation of gene sequencing and splicing are spot on. And I wouldn't be surprised if some of the scientists involved in the work are thinking nothing more than, "dire wolfs/wooly mammoths/sabertooth tigers/dinosaurs, cool!" They are geeks, and lets face it, those animals are cool to contemplate. But if you think that animal rights people aren't contemplating how to get them on the endangered species list, and how to use them to restrict or eliminate use/harvest/management of other animals, I think you are very naive.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8385011 04/11/2512:47 PM04/11/2512:47 PM
We have been experimenting cloning farm animals for decades now. Messing around with extinct wildlife is truly interesting but the scary part is a human can also be cloned. In all countries humans are supposed to be off the list, but with countries not trusting the others, who knows what might be happening. Technology does not always create good results. Food for thought
TILL THAT DAY.....
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8385080 04/11/2503:06 PM04/11/2503:06 PM
"But if you think that animal rights people aren't contemplating how to get them on the endangered species list, and how to use them to restrict or eliminate use/harvest/management of other animals, I think you are very naive."
How about we turn this around. Now there is no need for an endangered species list at all, since we can bring anything back we want.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: KeithC]
#8385651 04/12/2510:36 AM04/12/2510:36 AM
It already seems like there's two of them...that's enough!
But the expertise being gained here I think could be very useful to mankind. Think about the couples that have one or more of the nearly 1000 genetic diseases that are choosing not to have kids because of that. They could potentially edit out the faulty base pairs replicated in a gene and from there on out the family is free of a curse. I'll bet there's more applications than that too.
Last edited by beaverpeeler; 04/12/2510:37 AM.
My fear of moving stairs is escalating!
Re: Dire Wolves cloned (extinct thousands of years)
[Re: beaverpeeler]
#8385698 04/12/2511:52 AM04/12/2511:52 AM
It already seems like there's two of them...that's enough!
But the expertise being gained here I think could be very useful to mankind. Think about the couples that have one or more of the nearly 1000 genetic diseases that are choosing not to have kids because of that. They could potentially edit out the faulty base pairs replicated in a gene and from there on out the family is free of a curse. I'll bet there's more applications than that too.
I agree that this technology is very useful for man too. That's not saying that bad or careless people could not cause disasters with this technology. I think overall, it will improve life for most people.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8385702 04/12/2511:58 AM04/12/2511:58 AM
"But if you think that animal rights people aren't contemplating how to get them on the endangered species list, and how to use them to restrict or eliminate use/harvest/management of other animals, I think you are very naive."
How about we turn this around. Now there is no need for an endangered species list at all, since we can bring anything back we want.
WHOA! For a guy from Minnesota you're thinking is spot on! What a great "argument" in a Federal Court!......... And I never mention that I'm from Colorado to anyone with a thought process. (At least I came here from Wyoming)!!!!
Last edited by wy.wolfer; 04/12/2505:14 PM.
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8385842 04/12/2505:17 PM04/12/2505:17 PM
Should now be no more endangered species list.Allow all trapping with no restrictions for all species of animals.
That’s just bad management. Guys on horses with .30-30’s near wiped North America clean of anything to eat for a while, and human populations were a lot lower then. If the same thing were to happen with the current population levels and the technology available, most animals would be looking at extinction pretty rapidly
Re: Dire Wolves cloned (extinct thousands of years)
[Re: AK Timber Tramp]
#8385883 04/12/2507:12 PM04/12/2507:12 PM
Should now be no more endangered species list.Allow all trapping with no restrictions for all species of animals.
That’s just bad management. Guys on horses with .30-30’s near wiped North America clean of anything to eat for a while, and human populations were a lot lower then. If the same thing were to happen with the current population levels and the technology available, most animals would be looking at extinction pretty rapidly
Yep. No idea how a supposed sportsmen can keep posting about wanting to extirpate entire species. First it was wolves and now everything. Seasons and limits exist for a reason. In my state we have healthy populations of all the trappable species, and so have long seasons with no limits. But just imagine no limit on, say marten and fisher in MN, or marten in NY. It wouldn't be but a few years until they were all gone.
And it sure makes trappers in general look bad when people post stuff like that.
Proudly banned from the NTA.
Out on the road that lies before me now There are some turns where I will spin
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8385891 04/12/2507:38 PM04/12/2507:38 PM
I call BS on the whole article until they show me a wolf-like canine weighing 350 lbs and standing 60 inches at the shoulder.
And I work in "science", although not DNA research. I've done a lot of journal article reviews in the past 5 years (lots and lots of peer-reviewed journals out there and its a business, with the big name journals the most costly one out to get published in, especially if you want your work to be "open access" so anyone can read it). I can tell you there is as much "faith" in a lot of science as there is in various religious dogma.Various scams work by pushing the envelope a bit at a time until that "edge" is "accepted" and then later almost no one will challenge it.
As if "Jurassic Park" is real...
"And God said, Let us make man in our image �and let them have dominion �and all the creatures that move along the ground". Genesis 1:26
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8386270 04/13/2501:51 PM04/13/2501:51 PM
Then the BS/scam meter just spins up some more, doesn't it. Bred back and forth some of the biggest gray wolves out there until you get some that typically push toward 150, and kazam, we have a "dire wolf"
"And God said, Let us make man in our image �and let them have dominion �and all the creatures that move along the ground". Genesis 1:26
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8386300 04/13/2502:48 PM04/13/2502:48 PM
There's grey wolves that have weighed over 170 pounds and domestic dogs, that have weighed over 340 pounds. 150 pounds is not very big. The biggest domestic dogs are over twice the weight of a dire wolf.
Keith
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8386303 04/13/2503:12 PM04/13/2503:12 PM
P.S. Here' some diddy about how much it costs to get "open access" in peer-reviewed journals so anyone can read an article instead of just people or insinuations that have subscriptions.
In 2021, we had an manuscript that dealt with the analysis of a new, broad U.S. mapping effort across about 35 years and the changes that we found using one of its components. Fairly broad stuff but because it dealt with the whole CONUS and covered the amount of time that it did AND it was from a government research group, we thought that The Proceedings of the National Academy of Sciences USA (or PNAS as its known) might be interested in it. That's where I submitted it first, knowing that it was probably a long shot but we'll try. They ended up deciding not to send the manuscript out for review but in the couple of weeks or so that it took for them to tell us "no thanks", I had looked up their "open access" price.
If I remember correctly, it was $9.500
The next place we sent the manuscript was to a "tier 2" Nature venue. Nature (actually the publishing company is now Springer Nature, a UK company, at least the Nature part) was out of our league but their next step down is a line of journals that lead with "Nature" and then the theme of the research, such as "Nature Geoscience". They also decided not to send the manuscript out for review but I checked out their "open access" price. They were just under $5,000 a pop in 2021.
I think the reason the above (and another Nature - name your theme) journal didn't send this manuscript out for review was that there wasn't enough "blood in the streets" for their tastes. The paper finally got accepted in a "common people" peer-reviewed operation that has several hundred themed open access journals. Most "cool kid" authors who get in Science, PNAS, or Nature wouldn't even consider getting published with this large venue company because they are just "paper mills" that charge for publications and have very fast turn arounds from submission to possible publication. Of course those folks don't see their hypocrisy in publishing with the "prestigious" folks who charge nice coin for institutional subscriptions or the high "open access' fees such as those I've listed above. I find that thinking rather...amusing...
"And God said, Let us make man in our image �and let them have dominion �and all the creatures that move along the ground". Genesis 1:26
Re: Dire Wolves cloned (extinct thousands of years)
[Re: someGuyInKansas]
#8388418 04/17/2503:57 AM04/17/2503:57 AM
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